In modern analytical research and pharmaceutical manufacturing, verifying compound purity, identifying trace impurities, and quantifying active constituents demand unmatched precision. Chromatogen Analytical Solutions offers world-class LC-MS (Liquid Chromatography-Mass Spectrometry) and LC-MS/MS analysis services to support pharmaceutical companies, R&D organizations, biotech firms, and academic institutions across Karnataka and India.
Combining high-resolution liquid chromatography separation with ultra-sensitive mass spectrometry detection, our advanced laboratory delivers accurate, reproducible, and audit-ready analytical testing tailored to your strict project timelines.
Comprehensive LC-MS Analytical Services Offered
At Chromatogen, we provide an extensive suite of LC-MS testing capabilities designed to address complex chemical challenges at every stage of product development:
1. Impurity Profiling & Structural Elucidation
- Identification and characterization of unknown organic impurities, degradation products, and related substances in Active Pharmaceutical Ingredients (APIs) and drug formulations.
- Exact mass determination and fragment structure elucidation following ICH Q3A/Q3B guidelines.
2. Method Development & Method Validation
- Custom LC-MS and LC-MS/MS analytical method development for challenging or non-chromophoric molecules.
- Full analytical method validation covering Specificity, Linearity, Accuracy, Precision, LOD/LOQ, and Robustness in compliance with ICH Q2(R1) standards.
3. Trace & Genotoxic Impurity Analysis
- Ultra-trace level detection and quantification down to parts-per-billion (ppb) or parts-per-trillion (ppt).
- Specialized screening for nitrosamines, mutagenic impurities, and process-related byproducts.
4. Extractables & Leachables (E&L) Testing
- Comprehensive characterization of organic compounds migrating from primary container closure systems, medical devices, and manufacturing equipment into liquid formulations.
5. Custom Quantitative & Qualitative Testing
- Routine analytical testing, chemical fingerprinting, stability-indicating assays, and batch release testing for research and industrial applications.
Industries We Serve
- Pharmaceuticals & Biopharmaceuticals: API testing, metabolite identification (MetID), stability testing, and regulatory filings.
- Agrochemicals & Fine Chemicals: Active substance assay, pesticide residue profiling, and intermediate reaction monitoring.
- Environmental & Water Testing: Detection of trace micro-pollutants, polar pesticides, and per- and polyfluoroalkyl substances (PFAS).
- Food & Nutraceuticals: Mycotoxin screening, food authenticity verification, and nutritional supplement quality assurance.
- Academic & Contract R&D: Custom analytical support, structural validation for synthetic compounds, and publication-ready characterization data.
Technical Highlights & Capabilities
| Parameter | Capability / Specification |
| Separation Techniques | HPLC, UHPLC (Reverse Phase, Normal Phase, HILIC) |
| Ionization Sources | Electrospray Ionization (ESI), Atmospheric Pressure Chemical Ionization (APCI) |
| Detection Modes | Full Scan, Selected Ion Monitoring (SIM), Multiple Reaction Monitoring (MRM), Product Ion Scan |
| Sensitivity Limits | Trace-level detection down to ppb / ppt ranges |
| Compliance Standards | USP, IP, EP, BP, JP, ISO/IEC guidelines |
Why Choose Chromatogen for Your LC-MS Analysis?
- State-of-the-Art Instrumentation: Equipped with modern LC-MS and high-resolution mass spectrometers capable of resolving complex chemical matrices.
- Experienced Scientific Team: Lead by expert analytical chemists with extensive industry backgrounds in structural elucidation and method validation.
- Rapid Turnaround Time: Expedited testing options to keep your research, batch releases, and regulatory submissions on schedule.
- Audit-Ready Reporting: Detailed, transparent, and fully compliant analytical reports suitable for regulatory submissions (FDA, EMA, DCGI).
- Central Location in Mysuru: Strategically based in the Hebbal Industrial Area, providing seamless testing services to clients across Mysuru, Bengaluru, and nationwide.
Request Your LC-MS Analysis Consultation Today
Partner with Chromatogen Analytical Solutions for accurate, reliable, and compliant LC-MS analytical testing services.
- Address: #225, JCK Industrial Park, Nearby Chamundi Ceramics, Hebbal Industrial Area, Mysuru, Karnataka – 571606
- Phone: +91 76762 41735 / +91 99802 35464
- Email: chromatogen@gmail.com
- Website: chromatogen.in
